10. Los Angeles

The higher annual salaries are upstate in Silicon Valley and the Bay Area, but in the Los Angeles area, the average unadjusted annual salary of $98,346 ranks fourth in the U.S., behind New York, San Jose and San Francisco. But the adjusted salary, $80,939, ranks 12th among the top 15 cities in Indeed's data.

IT security specialists in LA pull in an average annual unadjusted salary of $104,584.

Meanwhile, the median monthly rent for a two-bedroom apartment is $3,021, according to the website Rent Jungle.